Naslov (srp)

Sinteza, karakterizacija i potencijalna citotoksičnost O,O'-dialkil-(S,S)-etilendiamin-N,N'-DI-2-(4-metil)-pentanoati i odgovarajućih paladijum(II), platina(II) i platina (IV) kompleksa: doktorska disertacija

Autor

Vujić, Jelena M., 1983-

Doprinosi

Trifunović, Srećko R., 1954-
Kaluđerović, Goran N.
Sabo, Tibor J., 1958-
Arsenijević, Nebojša, 1958-
Petrović, Biljana V., 1970-

Opis (srp)

Прилози. Умножено за одбрану. ПРИРОДНО-МАТЕМАТИЧКИ ФАКУЛТЕТ, Универзитет у Крагујевцу., 2012, др хемијских наука. Извод ; Summary. Библиографија: листови 101-107.

Opis (eng)

This works describes synthesis, characterization and potential cytotoxity of O,O'- -dialkyl-(S,S)-ethylenediamine-N,N'-di-2-(4-methyl)-pentanoic acid, [(S,S)-H4eddl]Cl2, as well as their corresponding palladium(II), platinum(II) and platinum(IV) complexes. Esters (S,S)-R2eddl·2HCl (R = ethyl, n-propyl, n-butyl and n-pentyl) were obtained by instillation of thionyl chloride in an appropriate absolute alcohol, and then refluxing with addition of (S,S)-ethylenediamine-N,N'-di-2-(4-methyl)-pentanoic acid. All of the esters were obtained as dihydrochlorides: (S,S)-Et2eddl·2HCl, (S,S)-Pr2eddl·2HCl, (S,S)-Bu2eddl·2HCl, (S,S)-Pe2eddl·2HCl. Esters were characterized by elemental analysis, IR and NMR spectroscopy, and in the case of (S,S)-Pr2eddl·2HCl the structure was confirmed by X-ray structural analysis.

Jezik

srpski

Datum

2012

Licenca

Ovo delo je licencirano pod uslovima licence
Creative Commons CC BY-NC 2.0 AT - Creative Commons Autorstvo - Nekomercijalno 2.0 Austria License.

CC BY-NC 2.0 AT

http://creativecommons.org/licenses/by-nc/2.0/at/